Malkolak Knowledge Centre

Malkolak Knowledge Centre (Malkolak) is a registered Trust formed in March 2005 promoted by a strong team of professionals with proven experience in different domains of knowledge, with several distinctive achievements to their credit. They are committed to this effort, with a Mission and clear commitment to realise the strong potential that exists to match knowledge and opportunity in India and abroad, to realize enormous wealth in Frontier areas. The Trust has members who worked both in the public domain and private sector at the higher echelons and gained vast experience in various fields. Sharing a common dream, the founders of the Trust conceived this knowledge centre as a catalyst institution. The knowledge centre focuses primarily on research and development in various frontier areas of technology and also humanities and social sciences.At present, Malkolak Core team comprises of a committed pool of resource persons, scientists and researchers involved with the activities in specified areas of study. Apart from full time team in place, we take guidance and intellectual support from many distinguished and eminent individuals and scientists both from India and abroad. Malkolak has a considerably good network of scientists both from India and abroad from different emerging areas of Science and Technology such as Nanotechnology, Biotechnology, Space technology, Medical fields etc.PROJECTS ON HAND WITH MALKOLAK KNOWLEDGE CENTRE 1.Mutant Phage Library Technology for rapid diagnostics: 2.Commercialization of anti-viral compounds - New Lead molecules for Malaria3.Biosensor to determine potassium concentration in human blood serum-4.A novel potentiometric cholesterol sensor for the quantitative estimation of total cholesterol in human blood serum .Other Commercialization of Product and process Patents with scientists of Malkolak:I.Isolation and purification of heparin from fish wasteII.Extraction of Anti-viral compounds obtained from marine animal.III.Identification, isolation and characterization of active compounds from the Indian green mussels to develop drugs.IV.Purification and characterization of compounds with anti-malarial activity from the extract of the Indian green mussel.V.Purification and characterization of a DC-stimulatory compound from the extract of the Indian green mussel.VI.Novel Molecules to Develop Drug for the treatment of Osteoporosis.VII.A Novel Molecule for Inducing Differentiation of Dendritic Cells.VIII.Indian Green Mussel as a Source of Anti HIV-Activity.IX.The extract of Indian green mussel (Perna viridis) inhibits growth of Mycobacterium tuberculosis.X.The extract of Indian green mussel (Perna viridis) shows an activity that inhibits replication of the Gemini virus.XI.Development of Nutraceutical products related to Anti-AgingWeight ManagementDigestiveAnti-inflammatoryCalming and SleepImmune-modulators/suppressorsMemory EnhancersAphrodisiacsProject Title: Isolation and purification of heparin from fish wasteHeparin, a well known saulfated polysaccharide with potent anti-coagulant and anti-lipaemic actions, has been used clinically for the past 50 years. Sulfated polysaccharides provide a broad biochemical interest, because of their wide occurrence in animals and plants and due to their biological activities as blood anticoagulant and connective tissue stimulant.